Antioxidant Defenses in the Brains of Bats during Hibernation
نویسندگان
چکیده
منابع مشابه
Antioxidant Defenses in the Brains of Bats during Hibernation.
Hibernation is a strategy used by some mammals to survive a cold winter. Small hibernating mammals, such as squirrels and hamsters, use species- and tissue-specific antioxidant defenses to cope with oxidative insults during hibernation. Little is known about antioxidant responses and their regulatory mechanisms in hibernating bats. We found that the total level of reactive oxygen species (ROS) ...
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Differential expression of Akt, PPAR , and PGC-1 during hibernation in bats
The effects of hibernation on the expression of Akt (protein kinase B), the peroxisome proliferator-activated receptor gamma isoform (PPARγ), and the PPARγ coactivator PGC-1 were assessed in seven tissues of the little brown bat, Myotis lucifugus. Western blotting revealed that the levels of active phosphorylated Akt were strongly reduced in brain, kidney, liver, and white adipose during torpor...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0152135